The Brain Prize Resource on Rett syndrome
The Brain Prize is the world’s largest prize for neuroscience that recognises one or more individuals who have made outstanding contributions to neuroscience. As well as being a celebration of neuroscience, The Brain Prize provides the Lundbeck Foundation with a unique opportunity to raise awareness of brain research and the burden of brain diseases.
The Rett film collection
In 2020 Professors Huda Zoghbi and Adrian Bird were awarded The Brain Prize for their pioneering work on Rett syndrome, a devastating brain disease that affects girls in their early childhood. What inspired Huda Zoghbi and Adrian Bird to work on Rett syndrome and what were their scientific journeys? What are the symptoms of Rett syndrome and what causes it? What is it like to live with a child that has Rett syndrome and is there hope for a cure?
To answer these questions the Lundbeck Foundation has developed the Rett Film Collection which profiles the 2020 Brain Prize winners and provides an in-depth perspective on the science of Rett syndrome- its symptoms, the discovery of its genetic basis, disease mechanisms and hopes for a cure. We also profile Mille and her family to illustrate what it is like to live with Rett syndrome.
Dr Huda Zoghbi is Professor of genetics at Baylor College of Medicine and Texas Children’s Hospital in Houston. Huda Zoghbi was born...
Sir Adrian Bird was born and grew up in England. He received his PhD from Edinburgh University in 1970 for describing how the...
The Rett educational film
In this film Huda Zoghbi and Adrian Bird describe the symptoms of Rett syndrome and how mutations in the MeCP2 gene were identified as the cause of Rett syndrome. They also describe the function of MeCP2, how mutations in MeCP2 impact brain function and how their scientific discoveries may pave the way for a cure.
The 2020 Brain Prize ceremony film
This film profiles Huda Zoghbi and Adrian Bird and describes what inspired and motivated the two Brain Prize winners of 2020 to become scientific researchers who dedicated their careers to studying Rett syndrome. The film was shown during The Brain Prize celebration.
The Rett case story: Mille
The Rett Film Collection also profiles Mille, a girl with Rett syndrome, and her family to reveal what it is like to live with Rett syndrome.
Read more about Mille's life with Rett Syndrome:
9-årige Mille har Rett syndrom. En sjælden, medfødt og udviklingshæmmende hjernesygdom, der ikke kan kureres.
