Circuits for Movement
Silvia Arber, Martyn Goulding and Ole Kiehn have revolutionized our understanding of the fundamental cells and circuits underlying mammalian body movement and have defined the importance of these elements in health and disease.
The Brain Prize Winners 2022
About Locomotion
There is nothing more fundamental to animal life than movement and a core role of the central nervous system is to successfully produce such coordinated movement.
Defining the circuits and the roles of neuronal classes that produce movements is critical; both for a basic understanding of how the nervous system works and, as importantly, for understanding what goes wrong in the various medical conditions affecting normal movement. Silvia Arber, Martyn Goulding and Ole Kiehn and have revolutionized our understanding of the fundamental cells and circuits underlying mammalian body movement and have defined the importance of these elements in health and disease.
The Information Pack for The Brain Prize 2022:
Here you can read a synopsis of the award-winning research that was performed by Silvia Arber, Martyn Goulding and Ole Kiehn. The information pack also contains the short autobiographies of the three winners and an article written by David McLean, Associate Professor of Neurobiology and Neuroscience at Northwestern University, USA about the field of movement control.
Brain Prize 2022 Explainer: How we move. A Lundbeck Foundation Documentary
In this full-length documentary, you will hear about how the motor system, the parts of the nervous system devoted to controlling movement, works. You will learn about how the spinal cord controls locomotion and how circuits in the spinal cord are, in turn, controlled by signals from the brainstem. Silvia Arber, Martyn Goulding and Ole Kiehn talk about how they have harnessed new technologies for studying the brain to identify specific types of neuron and how they control different aspects of movement such as speed, gait, stopping, starting, turning and skilled movements of the arms and hands. They share their hopes for using this new knowledge to restore movement following injury or disease.
The Brain Prize 2022 Announcement film:
Lene Skole, CEO of the Lundbeck Foundation introduces the Brain Prize and the goals of the Lundbeck Foundation. Professor Richard Morris Chair, of The Brain Prize selection committee, talks about the process of selecting the winners and explains what the selection committee found so compelling about the work of Silvia Arber, Ole Kiehn and Martyn Goulding.
The Brain Prize 2022 Ceremony film:
This film is a personal portrait of the three Brain Prize winners. It describes their upbringing, role models and their motivations for becoming neuroscientists.
Circuits for Movement – The Brain Prize Webinar Series 2022/3
As part of our scientific outreach activities related to The Brain Prize, the Lundbeck Foundation organizes The Brain Prize webinars- a series of online seminars that are free to attend and that are related to the topic of the current year’s Brain Prize. In 2022 The Brain Prize was awarded to Silvia Arber, Martyn Goulding and Ole Kiehn for their work on the circuits that control movement. This year’s webinar series consists of 6 webinars from leaders in the field of movement control. Each webinar consists of three talks followed by an open discussion and Q&A session.
The program with links to the webinar can be found below.
Program and Speakers
1. Brain Prize Winners webinar (June 9th 2022)Silvia Arber (Biozentrum & FMI)
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2. Brainstem (September 9th 2022)David Kleinfeld (UCSD)
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3. Somatosensation (October 28th 2022)Mackenzie Mathis (EPFL)
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4. Spinal interneurons (December 14th 2022)Abdel El Manira (Karolinska Institutet)
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5. Basal Ganglia (January 26th 2023)Rui Costa (Zuckerman Mind Brain Behavior Institute, Columbia University)
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6. Spinal cord repair (March 14th 2023)Martin Schwab (ETH, Zurich)
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Educational
Amongst their many discoveries, The Brain Prize winners of 2022 have identified neurons in the brainstem that can control the initiation and termination of movement. This paves the way for the potential use of targeted stimulation strategies to improve movement in Parkinson’s disease. To obtain free educational material about Parkinson’s disease visit Neurotorium, a free online knowledge platform on the brain and its diseases. The Parkinson's disease pages at Neurotorium contains articles, slide decks, illustrations, expert interviews, infographics, and shared decision-making pamphlets. All content is scientifically reviewed, and the platform is overseen by an editorial board consisting of leading experts. Neurotorium is founded by the Lundbeck Foundation.
News in relation to The Brain Prize 2022
