Model of the first relay station in the gut-brain communication

Associate Professor

University of Copenhagen

Jens Christian Rekling, associate professor, Department of Neuroscience, University of Copenhagen, has been awarded a Lundbeck Foundation LF Experiments research grant worth DKK 1,999,632.

The gut converse with the brain like no other organ, informing the central nervous system about feeding status. Studying this communication has been difficult since the involved systems are widely separated and difficult to access experimentally. The project aims to provide a better understanding of how signalling systems, involved in satiety and hunger, transmit sensory information from the gut. The model can be used in drug discovery projects that target gut-brain signalling systems involved in metabolic disease, like obesity.