Experiment

Petr Bednarik

Spectroscopic deuterium imaging to quantify aerobic and anaerobic metabolism in the human brain

Senior researcher
Amager and Hvidovre Hospital

Petr Bednarik, senior researcher, Danish Research Centre for Magnetic Resonance, Amager – Hvidovre Hospital, has been awarded a Lundbeck Foundation LF Experiments research grant worth DKK 1,999,200.

This project proposes a proof-of-concept experiment to showcase the potential of a novel quantitative mapping method: deuterium magnetic resonance spectroscopic imaging (DMRSI). The project aims to tune and implement DMRSI methodology using a 7T MR scanner to achieve comprehensive metabolic modeling in the human brain with high spatial specificity. Hoping to set the stage for future metabolic brain studies, measuring how aging, neurodegenerative and metabolic disorders impair the brain’s aerobic and anaerobic metabolism, using non-harmful tracers without the need for specialized hardware.

Petr