Rita Monteiro
What are neural enhancers made of? A novel approach to characterise enhancer-specific proteomes
Rita Monteiro, assistant professor, Center for Stem Cell Research and Developmental Biology (DANSTEM), University of Copenhagen, has been awarded a Lundbeck Foundation LF Experiments research grant worth DKK 1,999,131.
Enhancers are DNA sequences that regulate gene expression and can do so from great genomic distances. More than 40 years since their discovery, the means by which they select specific genes and regulate their transcription remains unknown. In this proposal, Rita Monteiro seeks to address the question of their activity by providing a complete picture of the proteins that bind specific enhancers. Thus, hoping to unravel new features of general transcriptional regulation by enhancers while providing important insight into the role of these sequences in neural development and disease.
